Chapter 10
Protein Informatics and Cheminformatics
Exercises
1. What is the role of information technology in determination of protein properties?
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2. What type of protein raw data is used for computationally extracting information about the protein?
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3. Name any two common tools for domain prediction.
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4. What is the significance of cheminformatics?
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5. Which of the following is not a rule in Lipinski’s rule of five (RO5)?
(a) No more than 10 hydrogen bond receptors
(b) Partition coefficient logP of less than 5
(c) Not more than 5 hydrogen bond donors
(d) Molecular weight above 500g/mol
Answer:
6. Which of the following properties of protein is not included in primary structure prediction?
(a) Aliphatic index
(b) Fold prediction
(c) Instability index
(d) Isoelectric point
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